How Fish Oil Transformed Heart Health and Beyond in 2026

Fish oil, widely known as omega-3, remains one of the most popular dietary supplements worldwide. Often promoted for its heart-protective benefits, it is also believed to improve mood, reduce inflammation, and support general health.

The modern fascination with fish oil began in the 1970s, when researchers uncovered the heart-healthy properties of omega-3 fatty acids. Derived from oily fish, fish oil is packed with two key omega-3s: EPA and DHA. These fatty acids help maintain cell membrane flexibility, ensuring proper cell function.

Fish oil's mild anti-inflammatory effects have been shown to ease joint tenderness and morning stiffness in people with inflammatory arthritis. Some studies also suggest it may modestly improve symptoms of clinical depression when combined with antidepressants.

For heart health, omega-3s are particularly effective at lowering triglycerides. A 2023 study found that a daily intake of over 2 grams of EPA and DHA is needed to achieve meaningful reductions. In Australia, high-dose prescription EPA treatments like Vazkepa became available under the Pharmaceutical Benefits Scheme (PBS) in early 2025, following its introduction in late 2024. By January 2026, around 15% of eligible high-risk cardiovascular patients were using it, supported by updated guidelines from the National Heart Foundation in mid-2025.

Most people tolerate fish oil well, though some experience minor side effects like a fishy aftertaste, mild nausea, or diarrhoea.

Fish oil continues to be a widely used supplement, backed by decades of research into its health benefits. With improved access to high-dose treatments in countries like Australia, its role in managing heart disease and inflammation is becoming more established. For most, it remains a safe option with manageable side effects.