Mandy Moore joins fight against RSV after her sons' harrowing battles

Respiratory syncytial virus (RSV) surged sharply in Germany and the US after pandemic restrictions eased. The 2021–2022 season saw a major spike, with cases peaking in winter 2022–2023 before settling back to pre-pandemic levels. Now, actress Mandy Moore is working with Sanofi to raise awareness about RSV protection for infants through their Beyfortus campaign.

RSV typically spreads in colder months, from October to March in the US, alongside flu and other seasonal viruses. Data from the RKI and CDC show children under five face the highest risk, with two-thirds catching RSV by their first birthday if unprotected. Severe cases can lead to breathing difficulties, retractions, and even respiratory failure—a life-threatening emergency.

Globally, RSV causes over 3.6 million hospitalisations and around 100,000 deaths in young children each year. However, monoclonal antibodies like Beyfortus can cut hospitalisation risk by over 70 percent. Pregnant women can also pass on protection by getting the RSV vaccine, shielding their baby for the first six months.

Mandy Moore's two sons, August 'Gus' Harrison and Oscar 'Ozzy' Bennett, both contracted RSV in 2023. Her youngest, daughter Louise 'Lou' Everett, was born in September—just before the usual RSV season. To prevent infection, Lou received the monoclonal antibody Beyfortus.

RSV remains a serious threat to young children, but prevention options now exist. Monoclonal antibodies and maternal vaccination offer strong protection during the high-risk winter months. Moore's campaign aims to highlight these measures as cases return to expected seasonal patterns.