World's oldest person, 117, leaves legacy in longevity science

Maria Branyas Morera, the world’s oldest known person, has died at the age of 117. Before her passing in 2024, she contributed to scientific research that explored the secrets of her extraordinary longevity. Her case has now provided new insights into ageing and health. Branyas was a supercentenarian, living well beyond 110 years. Researchers studied her genetic makeup and gut health to understand her long life. They discovered protective genetic variants that shielded her from common age-related diseases.

Her gut microbiome was remarkably diverse, resembling that of someone far younger. Scientists compared it with samples from people who had not reached 110. The findings suggested a strong link between her gut bacteria and her resilience. Branyas followed a Mediterranean diet and ate yoghurt daily, habits that may have supported her microbiome. Before her death, she agreed to donate samples for further study. The results were later published in the journal *Cell Reports Medicine*.

The research into Branyas’s longevity highlights the role of genetics and gut health in ageing. Her microbiome and lifestyle choices have given scientists valuable data for future studies. The findings could help explain why some people live far longer than average.